Selcia

Analytical Services

Every product synthesised by Selcia chemists undergoes rigorous verification of its structure and purity. From the beginning of April 2006, the group has operated according to the principles of Good Laboratory Practice providing fully GLP certified QC data and documentation. This capability, including Europe’s only GLP-certified LC-NMR contract research facility, allows full support of projects leading to regulatory submission and beyond.

Our services include structural analysis, analytical and bioanalytical method development for regulatory purposes as well as support for ADMET/DMPK and environmental fate studies of pharmaceutical, crop science and related products. We also offer impurity profiling of active pharmaceutical ingredients for clinical trial and regulatory purposes, metabolic profiling and biomarker identification and discovery technologies based on novel applications of analytical techniques. Selcia’s analytical capabilities include:

High Field NMR: 300, 400, and 500 MHz spectrometers

  • Multinuclear Analysis (1H, 2H, 3H, 13C, 15N, 19F, 31P)
  • LC-NMR (Standard Flow x 2 and Capillary-LC)
  • Flow NMR (Standard Flow x 2 and Capillary-LC)
  • HR-MAS NMR
  • Ultra high throughput flow NMR (proprietary)

LC-MS/MS System

  • GC-MS/MS capacity
  • Binary high pressure LC (capillary-LC capacity)
  • ESP, APcI, TSP, PSP, EI and CI ion sources

LC-MS Systems

  • Micromass Platform – Binary high-pressure LC (capillary-LC capacity) offering Electrospray, APcI, EI and CI ion sources
  • Finnigan Aqa – Binary high-pressure LC (capillary-LC capacity) offering Electrospray and APcI ion sources
  • Finnigan MSQ, binary high-pressure LC offering Electrospray and APcI ion sources
  • High throughput system (1000 analyses/day)

GC-MS System

  • Hewlett Packard with Gerstell Large volume PTV (biofluid analysis)

FT-IR Microscopy

  • Nicolet Protégé with Continuum Microscope
  • Diffuse reflectance

For more information on our analytical capabilities and services please contact us.