A flexible service tailored to your needsSelcia’s CEfrag™ screening service offers a fast and cost effective way to identify hits for your biological target, with clear Go/No-go decision points.

Contract Screening

With all our screening techniques we offer screening only or screening with follow-up medicinal chemistry packages.

All screening services at Selcia including CEfrag can be performed as part of an Integrated Drug Discovery package.

  Project phases & activities are costed out individually

Project Phases

With a team of highly experienced medicinal chemistry experts, we can turn your hit into a lead – and beyond, into a fully optimised clinical candidate.
 

  • Prioritise hits
    • Affinity - Ligand efficiency - Chemical attractiveness
  • Verify functional activity
  • SAR/Analogue
    • By catalogue (substructure/pharmacophore searching)
    • By synthesis
  • Integrated approach with Computer Assisted Drug Discovery
  • Optimisation: Increase molecular complexity
    • Fragment growing/merging/linking
    • Traditional medicinal chemistry

 

Please also refer to our Medicinal Chemistry page

Our business model is cost effective, based on fee-for-service. Each project will have a tailored quote with transparent pricing of project phases.

After the initial screen you will receive an interim report including structures. A full report with recommendations for follow up will be produced after IC50 determination.

 

Please contact us for further information. We will be pleased to arrange a teleconference or meeting with our technical experts.


CEfrag™ Fragment Screening
CEfrag™ Fragment Screening

Powerful New Fragment Screening Technology CEfrag™ Screen

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