High quality drug candidates are not possible without high quality data. We provide a comprehensive range of ADME, PK and bio-analytical services generating robust and reliable data.
Capabilities include:
- pKa/ADME predictive tools
- Physico-chemical properties (Log D, solubility, chemical stability)
- Metabolic stability (in microsomes and/or plasma)
- Distribution studies (plasma protein binding and PAMPA)
- Drug-drug Interactions (Cytochrome P450 inhibition e.g. CYP3A4)
- Cytotoxicity (e.g. HepG2)
- Bioanalysis (e.g. Quantitation of drug exposure, metabolite identification)
- In vivo pharmacokinetics (sub-contracted to a trusted and validated partner)
We work closely with you to develop an ADME program suited to your project. We have a flexible approach depending on your requirements and can modify protocols and develop custom assays in your preferred format.
Please contact us for further information. We will be pleased to arrange a teleconference or meeting with our technical experts.